Optimise trial hypertension

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August undefined, 2024

WebOct 1, 2024 · The OPTiMISE trial is a multi-disciplinary and multi-institution programme of work on optimising treatment for mild systolic hypertension in the elderly. Due an ageing … WebThe Optimising Treatment for Mild Systolic Hypertension in the Elderly (OPTIMISE) trial used a primary care–based, randomized, unblinded, parallel group, noninferiority design. …

Effects of Intensive Blood-Pressure Control in Type 2 …

WebThe 2024 Optimizing Treatment for Mild Systolic Hypertension in the Elderly (OPTiMISE) trial examined the safety of reducing blood pressure medications in older patients with … WebMay 26, 2024 · Design, setting, and participants: The Optimising Treatment for Mild Systolic Hypertension in the Elderly (OPTIMISE) study was a randomized, unblinded, noninferiority trial conducted in 69 primary care sites in England. Participants, whose primary care … how do you reseal a bath

Frontiers Blood Pressure Changes Following Antihypertensive ...

WebJun 3, 2024 · The OPTIMISE Randomized Clinical Trial: Deprescribing Antihypertensive Medications in Adults Aged 80 and Older and its Effect on Blood Pressure Sheppard J, et al. Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients with Hypertension Aged 80 Years and Older. WebApr 20, 2024 · This study used data from the OPTiMISE trial to examine whether short-term outcomes of deprescribing vary by drug class and dose of medication withdrawn. Methods: The OPTiMISE trial included patients aged ≥80 years with controlled systolic blood pressure (SBP; <150 mmHg), receiving ≥2 antihypertensive medications. This study compared SBP ... WebOct 4, 2024 · Stable dose of antihypertensive medications for at least 4 weeks prior to trial entry. In the investigator’s opinion, could potentially benefit from medication reduction … phone number for ring doorbell tech support

Cost-effectiveness of antihypertensive ... - University of Bristol

Deprescribing Antihypertensive Agents in the OPTIMISE Trial

WebThe present study tests the system's effectiveness in a randomized, controlled trial in diabetic patients with uncontrolled systolic hypertension. Of 244 subjects screened for eligibility, 110 (45%) were randomly allocated to the intervention (n = 55) or control (n = 55) group, and 105 (95.5%) completed the 1-year outcome visit. WebMay 3, 2024 · While in the SEPSIPAM trial, patients with history of hypertension had lower incidence of severe acute kidney injury (AKI) in the higher target group, patients with history of hypertension in the 65 trial had lower 90 days mortality in the low pressure group (median MAP 65 mmHg, adjusted odds ratio, 0.67; 95% CI, 0.49–0.85). how do you researchWebCost-effectiveness of antihypertensive deprescribing in primary care: a Markov modelling study using data from the OPTiMISE trial Sue Jowett, Shahela Kodabuckus, Gary A. Ford, F.D. Richard Hobbs, Rupert A Payne, James P. Sheppard * how do you research property history online

"WebSep 1, 2003 · According to these guidelines, supported by clinical study reports, diuretics and beta-blockers are recommended as the first-line medications in the treatment of … " - Optimise trial hypertension

Optimise trial hypertension

Optimising treatment for high blood pressure in the elderly

WebNov 27, 2024 · Over the years, a number of landmark clinical studies in the field of hypertension have been published, shaping how the disease is treated. Here are 5 that every pharmacist should know about: 1. DASH (1997)1. By the early 1990s it had been well-established that obesity, sodium intake, and alcohol consumption can influence blood … WebOPTiMISE Optimising Treatment for Mild Systolic hypertension in the Elderly OPTiMISE Patient Information Leaflet V1.1 13.12.16_RCT.docx IRAS ID: 212465 Page 5 of 12 OPTiMISE trial – Full details What is the Purpose of the Trial? The population is getting older (over 3 million people in the UK are aged 80

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WebOct 5, 2024 · The researchers of this study 1 aimed to establish whether reduction of one antihypertensive medication in adults over the age of 80, on two or more antihypertensive … WebThe OPTiMISE (Optimising Treatment for Mild Systolic Hypertension in the Elderly) trial sought to address this evi-dence gap through a randomized, open label, noninferiority trial …

WebMay 26, 2009 · The current study demonstrated the efficacy and safety of treating moderate or severe hypertension with triple therapy consisting of Aml/Val/HCTZ 10/320/25 mg. Initial treatment of hypertension with a dual-combination agent with complementary mechanisms of action may allow BP goals to be realized more quickly than adding single entities … WebThe NIH Systolic Blood Pressure Intervention Trial (SPRINT), an NHLBI-supported study, was designed to answer three important research questions about how treating to a lower systolic blood pressure target—less than 120 millimeters of mercury (mm Hg)—affects the cardiovascular system, kidneys, and brain.

WebOPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE) The OPTiMISE Study The aims of this study were: To safely reduce the amount of blood … WebCost-Effectiveness of Telemonitoring and Self-Monitoring of Blood Pressure for Antihypertensive Titration in Primary Care (TASMINH4) Hypertension The use of self-monitoring of blood pressure, with or without telemonitoring, to guide therapy decisions by physicians for patients with hypertension has been recently demonstrated to reduce …

WebJul 7, 2024 · OPTIMISE Trial: Impact of Antihypertensive Medication Reduction in Elderly Hypertensive Patients CiplaMed Home SPECIALITY General Medicine Cardiology Critical …

WebThe OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE) trial will target frail individuals with polypharmacy and comorbidity, and aim to establish whether a … phone number for river link to pay my billWebMay 12, 2024 · This study aimed to define the proportion and characteristics of patients eligible for hypertension trials conducted in older people. DESIGN: Cross-sectional study. SETTING: A total of 24... how do you research tactics in evonyWebJun 1, 2024 · Observed and expected serious adverse event rates in randomised clinical trials for hypertension: an observational study comparing trials that do and do not focus on older people Article... phone number for rmv massachusettsWebMay 28, 2024 · The OPTIMISE (Optimising Treatment for Mild Systolic Hypertension in the Elderly) study was a randomized, unblinded, noninferiority trial conducted in 69 primary … phone number for ring helpWebMay 3, 2024 · While in the SEPSIPAM trial, patients with history of hypertension had lower incidence of severe acute kidney injury (AKI) in the higher target group, patients with … how do you research somethingWebJun 28, 2024 · The original SNAP-HT trial was designed to assess feasibility and safety of a self-management digital intervention in the postnatal period, but exploring the impact of the intervention on BP was an important secondary outcome. 25 The finding in SNAP-HT of a persistently lower diastolic BP at 6 months, when almost all women had stopped … how do you research important topicsWebSep 1, 2024 · The aim of this trial is to examine whether antihypertensive medication reduction is possible in older patients without significant changes in blood pressure control at follow-up, and to determine if a reduction in medication can achieve a proportion of participants with clinically safe blood pressure levels at 12-week follow up. Introduction … phone number for rmv ma