WebBenralizumab is an interleukin-5 receptor α-directed cytolytic monoclonal antibody that directly depletes eosinophils. Its relative efficacy versus other IL-5-targeted treatments for patients with severe, uncontrolled asthma is not yet fully characterised. We performed a matching-adjusted indirect comparison (MAIC) of benralizumab versus mepolizumab … Web1 sep. 2012 · Matching-adjusted indirect comparisons (MAICs) use IPD from trials of one treatment to match baseline summary statistics reported from trials of another …
Matching‐adjusted indirect comparisons: Application to …
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(PDF) Modified Akaike Information Criterion (MAIC) for statistical ...
Web4 mei 2024 · Current MAIC approaches. A range of statistical techniques have been developed that attempt to address these challenges, such as extensions of network meta-analysis [], simulated treatment comparison [] and MAIC [4,5].MAIC methodology typically aims to reweight IPD from the experimental treatment in order to match the distribution at … WebThe Matching-Adjusted Indirect Comparison method (MAIC) is a recent methodology that allows to perform indirect comparisons between two drugs assessed in two different studies, where individual patients data are available in only one of the two studies, the data of the other one being available in an aggregate format only. Webmaic This package facilitates performing matching-adjusted indirect comparison (MAIC) analysis where the endpoint of interest is either time-to-event (e.g. overall survival) or … san francisco tango marathon 2016